A molecular gatekeeper that controls protein synthesis

 


Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of proteins that compact DNA. These new insights could form the basis for new approaches in cancer treatment, but they also critically extend the current understanding of protein biosynthesis.

The protein factories in cells—ribosomes—have a central task: during a process known as translation, amino acids are linked together according to messenger RNA, forming a growing peptide chain that later folds into a functional protein.

However, before a newly emerging protein can even begin to fold, it must be processed and transported to the correct location within the cell. As soon as it emerges from the ribosome, enzymes can remove its initial amino acid, attach small chemical groups, or determine to which cellular compartments the protein should be sent.

These activities already take place during translation and are essential for the correct function of most proteins. And this requires a coordinator.

Event Name : International Molecular Biologist Awards

Website Link: molecularbiologist.org/

Contact Mail ID : support@molecularbiologist.org

Nomination Link  : https://molecularbiologist.org/award-nomination/?ecategory=Awards&rcategory=Awardee


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#MolecularBiology #ProteinSynthesis #TranslationalControl #GeneExpression #CellRegulation #Ribosome #mRNA #Translation #CellSignaling #SystemsBiology #Biomolecular #Proteomics #RegulatoryNetworks

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